Hydroxycarboxylic acid receptor 1

id: hydroxycarboxylic-acid-receptor-1-277-5531322
title: Hydroxycarboxylic acid receptor 1
text: Hydroxycarboxylic acid receptor 1 (HCA1), formerly known as G protein-coupled receptor 81 (GPR81), is a protein that in humans is encoded by the HCAR1 gene. HCA1, like the other hydroxycarboxylic acid receptors HCA2 and HCA3, is a Gi/o-coupled G protein-coupled receptor (GPCR). The primary endogenous agonist of HCA1 is lactic acid (and its conjugate base, lactate). More recently, 3,5-dihydroxybenzoic acid has been reported to activate HCA1. Lactate was initially found to activate HCA1 on fat cel
brand slug: wiki
category slug: encyclopedia
description: Protein-coding gene in the species Homo sapiens
original url: https://en.wikipedia.org/wiki/Hydroxycarboxylic_acid_receptor_1
date created:
date modified: 2023-12-23T07:04:11Z
main entity: {"identifier":"Q18038714","url":"https://www.wikidata.org/entity/Q18038714"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e7/Ideogram_human_chromosome_12.svg","width":474,"height":189}
fields total: 13
integrity: 15

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