Huntingtin-interacting protein 1
id:
huntingtin-interacting-protein-1-274-15888517
title:
Huntingtin-interacting protein 1
text:
Huntingtin-interacting protein 1 also known as HIP-1 is a protein that in humans is encoded by the HIP1 gene. Hip-1 is a protein that interacts with the huntingtin protein. It is known to contain a domain homologous to the death effector domains (DED) found on proteins involved in apoptosis. It is believed that accumulation of high levels of the free form of this protein in the cell is one of the mechanisms by which neuron cell death is caused in Huntington's disease. The role of Hip-1 in caspas
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/Huntingtin-interacting_protein_1
date created:
date modified:
2023-03-03T23:51:20Z
main entity:
{"identifier":"Q18026895","url":"https://www.wikidata.org/entity/Q18026895"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/99/Ideogram_human_chromosome_7.svg","width":474,"height":189}
fields total:
13
integrity:
15