HORMA domain
id:
horma-domain-235-1949987
title:
HORMA domain
text:
In molecular biology, the HORMA domain is a protein domain that has been suggested to recognise chromatin states resulting from DNA adducts, double stranded breaks or non-attachment to the spindle and act as an adaptor that recruits other proteins. Hop1 is a meiosis-specific protein, Rev7 is required for DNA damage induced mutagenesis, and MAD2 is a spindle checkpoint protein which prevents progression of the cell cycle upon detection of a defect in mitotic spindle integrity.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/HORMA_domain
date created:
date modified:
2023-06-07T14:31:13Z
main entity:
{"identifier":"Q24778264","url":"https://www.wikidata.org/entity/Q24778264"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/b5/PDB_1go4_EBI.jpg","width":800,"height":600}
fields total:
13
integrity:
14