HOGA1
id:
hoga1-197-12638724
title:
HOGA1
text:
4-Hydroxy-2-oxoglutarate aldolase, mitochondrial (HOGA1) also known as dihydrodipicolinate synthase-like (DHDPSL) is an enzyme that in humans is encoded by the HOGA1 gene. The protein is one of the enzymes involved in metabolism of hydroxyproline to glyoxylate. The enzyme overactivity can form excessive glyoxylate from hydroxyproline. Glyoxylate is catabolised to oxalate, resulting in excess excretion of oxalate in urine, predisposing to oxalate stone; a condition known as primary hyperoxaluria
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/HOGA1
date created:
date modified:
2022-10-17T11:15:07Z
main entity:
{"identifier":"Q18048871","url":"https://www.wikidata.org/entity/Q18048871"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/2f/Ideogram_human_chromosome_10.svg","width":474,"height":189}
fields total:
13
integrity:
15