HLA-DOA

id: hla-doa-323-12462566
title: HLA-DOA
text: HLA class II histocompatibility antigen, DO alpha chain is a protein that in humans is encoded by the HLA-DOA gene. HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.
brand slug: wiki
category slug: encyclopedia
description: Protein-coding gene in the species Homo sapiens
original url: https://en.wikipedia.org/wiki/HLA-DOA
date created:
date modified: 2023-12-30T21:10:11Z
main entity: {"identifier":"Q18026933","url":"https://www.wikidata.org/entity/Q18026933"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/03/Ideogram_human_chromosome_6.svg","width":474,"height":189}
fields total: 13
integrity: 15

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