Hit to lead
id:
hit-to-lead-265-14345184
title:
Hit to lead
text:
Hit to lead (H2L) also known as lead generation is a stage in early drug discovery where small molecule hits from a high throughput screen (HTS) are evaluated and undergo limited optimization to identify promising lead compounds. These lead compounds undergo more extensive optimization in a subsequent step of drug discovery called lead optimization (LO). The drug discovery process generally follows the following path that includes a hit to lead stage: Target validation (TV) → Assay development →
brand slug:
wiki
category slug:
encyclopedia
description:
Stage of drug discovery
original url:
https://en.wikipedia.org/wiki/Hit_to_lead
date created:
date modified:
2023-12-09T01:56:37Z
main entity:
{"identifier":"Q13611503","url":"https://www.wikidata.org/entity/Q13611503"}
image:
fields total:
13
integrity:
14