Himbacine

id: himbacine-262-6454762
title: Himbacine
text: Himbacine is an alkaloid isolated from the bark of Australian magnolias. Himbacine has been synthesized using a Diels-Alder reaction as a key step. Himbacine's activity as a muscarinic receptor antagonist, with specificity for the muscarinic acetylcholine receptor M2, made it a promising starting point in Alzheimer's disease research. The development of a muscarinic antagonist based on himbacine failed but an analog, vorapaxar, has been approved by the FDA as a thrombin receptor antagonist.
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/Himbacine
date created:
date modified: 2023-01-29T01:02:56Z
main entity: {"identifier":"Q5765204","url":"https://www.wikidata.org/entity/Q5765204"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/1/16/Himbacine.svg","width":744,"height":1052}
fields total: 13
integrity: 15

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