Hereditary fructose intolerance
id:
hereditary-fructose-intolerance-323-3234766
title:
Hereditary fructose intolerance
text:
Hereditary fructose intolerance (HFI) is an inborn error of fructose metabolism caused by a deficiency of the enzyme aldolase B. Individuals affected with HFI are asymptomatic until they ingest fructose, sucrose, or sorbitol. If fructose is ingested, the enzymatic block at aldolase B causes an accumulation of fructose-1-phosphate which, over time, results in the death of liver cells. This accumulation has downstream effects on gluconeogenesis and regeneration of adenosine triphosphate (ATP). Sym
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Hereditary_fructose_intolerance
date created:
date modified:
2023-10-24T17:57:15Z
main entity:
{"identifier":"Q1609755","url":"https://www.wikidata.org/entity/Q1609755"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/ec/Fructose.svg","width":518,"height":235}
fields total:
13
integrity:
15