Hawkinsinuria
id:
hawkinsinuria-266-2589020
title:
Hawkinsinuria
text:
Hawkinsinuria is an autosomal dominant metabolic disorder affecting the metabolism of tyrosine. Normally, the breakdown of the amino acid tyrosine involves the conversion of 4-hydroxyphenylpyruvate to homogentisate by 4-hydroxyphenylpyruvate dioxygenase. Complete deficiency of this enzyme would lead to tyrosinemia III. In rare cases, however, the enzyme is still able to produce the reactive intermediate 1,2-epoxyphenyl acetic acid, but is unable to convert this intermediate to homogentisate. The
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Hawkinsinuria
date created:
date modified:
2022-04-25T02:49:06Z
main entity:
{"identifier":"Q5685180","url":"https://www.wikidata.org/entity/Q5685180"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/00/Hawkinsin.png","width":546,"height":531}
fields total:
13
integrity:
15