Hantzsch pyrrole synthesis
id:
hantzsch-pyrrole-synthesis-261-824506
title:
Hantzsch pyrrole synthesis
text:
The Hantzsch Pyrrole Synthesis, named for Arthur Rudolf Hantzsch, is the chemical reaction of β-ketoesters (1) with ammonia and α-haloketones (2) to give substituted pyrroles (3). Pyrroles are found in a variety of natural products with biological activity, so the synthesis of substituted pyrroles has important applications in medicinal chemistry. Alternative methods for synthesizing pyrroles exist, such as the Knorr Pyrrole Synthesis and Paal-Knorr Synthesis.
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical reaction
original url:
https://en.wikipedia.org/wiki/Hantzsch_pyrrole_synthesis
date created:
date modified:
2023-07-02T09:58:33Z
main entity:
{"identifier":"Q2198203","url":"https://www.wikidata.org/entity/Q2198203"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/9e/Hantzsch_Pyrrole_Synthesis_Scheme.png","width":1186,"height":583}
fields total:
13
integrity:
15