H3T45P

id: h3t45p-275-18617363
title: H3T45P
text: H3T45P is an epigenetic modification to the DNA packaging protein histone H3. It is a mark that indicates the phosphorylation the 45th threonine residue of the histone H3 protein. During apoptosis, H3T45 phosphorylation is required for structural changes inside the nucleosome that enable DNA nicking and/or fragmentation. The H3T45 residue appears to be a nucleosome gatekeeper, regulating DNA accessibility at transcription target sites. This could be a new regulatory network that coordinates gene
brand slug: wiki
category slug: encyclopedia
description: Epigenetic modification to the DNA packaging protein Histone H3
original url: https://en.wikipedia.org/wiki/H3T45P
date created:
date modified: 2023-12-01T02:15:36Z
main entity: {"identifier":"Q112072847","url":"https://www.wikidata.org/entity/Q112072847"}
image:
fields total: 13
integrity: 14

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