H-89
id:
h-89-318-18240259
title:
H-89
text:
H-89 is a protein kinase inhibitor with greatest effect on protein kinase A (PKA). H-89, derived from H-8 (N-[2-ethyl]-5-isoquinoline-sulfonamide), was initially believed to act specifically as an inhibitor of PKA, being 30 times more potent than H-8 at inhibiting PKA and 10 times less potent at inhibiting protein kinase G. It achieves this through competitive inhibition of the adenosine triphosphate (ATP) site on the PKA catalytic subunit. However, subsequent work has suggested a variety of add
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/H-89
date created:
date modified:
2023-11-07T12:27:56Z
main entity:
{"identifier":"Q5627831","url":"https://www.wikidata.org/entity/Q5627831"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/0a/H_89_dihydrochloride.svg","width":250,"height":85}
fields total:
13
integrity:
15