GYKI 52466
id:
gyki-52466-261-7719392
title:
GYKI 52466
text:
GYKI 52466 is a 2,3-benzodiazepine that acts as an ionotropic glutamate receptor antagonist, which is a non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >> 50 μM for AMPA-, kainate- and NMDA-induced responses respectively), orally-active anticonvulsant, and skeletal muscle relaxant. Unlike conventional 1,4-benzodiazepines, GYKI 52466 and related 2,3-benzodiazepines do not act on GABAA receptors. Like other AMPA receptor antagonists, GYKI 52466 has anticonvulsant and neu
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/GYKI_52466
date created:
date modified:
2022-06-30T23:51:46Z
main entity:
{"identifier":"Q5515088","url":"https://www.wikidata.org/entity/Q5515088"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/6e/GYKI_52466.svg","width":512,"height":626}
fields total:
13
integrity:
15