Gut-specific homing
id:
gut-specific-homing-275-12987624
title:
Gut-specific homing
text:
Gut-specific homing is the mechanism by which activated T cells and antibody-secreting cells (ASCs) are targeted to both inflamed and non-inflamed regions of the gut in order to provide an effective immune response. This process relies on the key interaction between the integrin α4β7 and the addressin MadCAM-1 on the surfaces of the appropriate cells. Additionally, this interaction is strengthened by the presence of CCR9, a chemokine receptor, which interacts with TECK. Vitamin A-derived retinoi
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Gut-specific_homing
date created:
date modified:
2023-08-18T11:03:31Z
main entity:
{"identifier":"Q18347702","url":"https://www.wikidata.org/entity/Q18347702"}
image:
fields total:
13
integrity:
13