Guanylin
id:
guanylin-191-11401050
title:
Guanylin
text:
Guanylin is a 15 amino acid peptide that is secreted by goblet cells in the colon. Guanylin acts as an agonist of the guanylyl cyclase receptor GC-C and regulates electrolyte and water transport in intestinal and renal epithelia. Upon receptor binding, guanylin increases the intracellular concentration of cGMP, induces chloride secretion and decreases intestinal fluid absorption, ultimately causing diarrhoea. The peptide stimulates the enzyme through the same receptor binding
region as the heat-
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Guanylin
date created:
date modified:
2023-11-08T13:03:56Z
main entity:
{"identifier":"Q24782982","url":"https://www.wikidata.org/entity/Q24782982"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/1/1b/1O8R.pdb.jpg","width":325,"height":275}
fields total:
13
integrity:
14