GRN-529
id:
grn-529-275-12861039
title:
GRN-529
text:
GRN-529 is a drug that was developed by Wyeth as a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5). A study conducted by Pfizer found that GRN-529 reduced repetitive behaviors without sedation and partially increased sociability in mouse models of autism. Another study conducted by Pfizer found a therapeutically relevant effect in animal models of depression. It is theorized to work by reducing glutamate receptor hyperactivity.
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/GRN-529
date created:
date modified:
2023-12-20T20:13:46Z
main entity:
{"identifier":"Q5514489","url":"https://www.wikidata.org/entity/Q5514489"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/a7/GRN-529.svg","width":512,"height":294}
fields total:
13
integrity:
15