Granulin

id: granulin-251-12500860
title: Granulin
text: Granulin is a protein that in humans is encoded by the GRN gene. Each granulin protein is cleaved from the precursor progranulin, a 593 amino-acid-long and 68.5 kDa protein. While the function of progranulin and granulin have yet to be determined, both forms of the protein have been implicated in development, inflammation, cell proliferation and protein homeostasis. The 2006 discovery of the GRN mutation in a population of patients with frontotemporal dementia has spurred much research in uncove
brand slug: wiki
category slug: encyclopedia
description: Protein-coding gene in humans
original url: https://en.wikipedia.org/wiki/Granulin
date created:
date modified: 2023-11-29T03:20:20Z
main entity: {"identifier":"Q18026495","url":"https://www.wikidata.org/entity/Q18026495"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/00/Ideogram_human_chromosome_17.svg","width":474,"height":189}
fields total: 13
integrity: 15

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