GPR143
id:
gpr143-179-17240038
title:
GPR143
text:
G-protein coupled receptor 143, also known as Ocular albinism type 1 (OA1) in humans, is a conserved integral membrane protein with seven transmembrane domains and similarities with G protein-coupled receptors (GPCRs) that is expressed in the eye and epidermal melanocytes. This protein encoded by the GPR143 gene, whose variants can lead to Ocular albinism type 1. The GPR143 gene is regulated by the Microphthalmia-associated transcription factor. L-DOPA is an endogenous ligand for OA1.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/GPR143
date created:
2007-11-26T03:40:56Z
date modified:
2024-09-05T05:40:52Z
main entity:
{"identifier":"Q18030245","url":"https://www.wikidata.org/entity/Q18030245"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/59/Ideogram_house_mouse_chromosome_X.svg","width":470,"height":200}
fields total:
13
integrity:
16