GoLoco motif
id:
goloco-motif-275-10288177
title:
GoLoco motif
text:
GoLoco motif is a protein structural motif. In heterotrimeric G-protein signalling, cell surface receptors (GPCRs) are coupled to membrane-associated heterotrimers comprising a GTP-hydrolyzing subunit G-alpha and a G-beta/G-gamma dimer. The inactive form contains the alpha subunit bound to GDP and complexes with the beta and gamma subunit. When the ligand is associated to the receptor, GDP is displaced from G-alpha and GTP is bound. The GTP/G-alpha complex dissociates from the trimer and associa
brand slug:
wiki
category slug:
encyclopedia
description:
Protein structural motif
original url:
https://en.wikipedia.org/wiki/GoLoco_motif
date created:
date modified:
2023-03-22T10:40:48Z
main entity:
{"identifier":"Q24738446","url":"https://www.wikidata.org/entity/Q24738446"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/ea/PDB_1kjy_EBI.jpg","width":800,"height":600}
fields total:
13
integrity:
15