GNE (gene)
id:
gne-gene-200-254049
title:
GNE (gene)
text:
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase is an enzyme that in humans is encoded by the GNE gene. The bifunctional enzyme, UDP-N-acetylglucosamine 2-epimerase regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. UDP-GlcNAc 2-epimerase activity is rate-limiting for the biosynthesis of sialic acid and is required for sialylation in hematopoietic cells. The activity of the enzyme can be controlled at the transcriptio
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in humans
original url:
https://en.wikipedia.org/wiki/GNE_(gene)
date created:
date modified:
2023-01-01T05:46:19Z
main entity:
{"identifier":"Q18034960","url":"https://www.wikidata.org/entity/Q18034960"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/d/de/Ideogram_human_chromosome_9.svg","width":474,"height":189}
fields total:
13
integrity:
15