GML-1

id: gml-1-219-4682917
title: GML-1
text: GML-1 is a TSPO ligand with anxiolytic activity. Its binding affinity to TSPO is comparable with PK11195. GML-1 is selective for TSPO versus the central benzodiazepine receptor. The compound GML-1 was the most active of a series of 1-arylpyrrolo[1,2-a]pyrazine-3-carboxamides, and its anxiolytic effects were examined using the open field test (OFT) and the elevated plus maze (EPM) test. The EPM test is a general anxiety test measuring the time spent by animals in the open or the enclosed arms. Wh
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/GML-1
date created: 2017-03-28T15:29:08Z
date modified: 2024-09-13T12:09:54Z
main entity: {"identifier":"Q30314417","url":"https://www.wikidata.org/entity/Q30314417"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/82/GML-1_structure.svg","width":512,"height":520}
fields total: 13
integrity: 16

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