GIR1 branching ribozyme
id:
gir1-branching-ribozyme-200-2211265
title:
GIR1 branching ribozyme
text:
The Lariat capping ribozyme is a ~180 nt ribozyme with an apparent resemblance to a group I ribozyme.
It is found within a complex type of group I introns also termed twin-ribozyme introns.
Rather than splicing, it catalyses a branching reaction in which the 2'OH of an internal residue is involved in a nucleophilic attack at a nearby phosphodiester bond.
As a result, the RNA is cleaved at an internal processing site (IPS), leaving a 3'OH and a downstream product with a 3 nt lariat at its 5' end.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/GIR1_branching_ribozyme
date created:
date modified:
2024-04-21T01:23:48Z
main entity:
{"identifier":"Q5513513","url":"https://www.wikidata.org/entity/Q5513513"}
image:
fields total:
13
integrity:
13