Genome-wide significance

id: genome-wide-significance-235-17207204
title: Genome-wide significance
text: In genome-wide association studies, genome-wide significance is a specific threshold for determining the statistical significance of a reported association between a given single-nucleotide polymorphism (SNP) and a given trait. The most commonly accepted threshold is p < 5 × 10−8, which is based on performing a Bonferroni correction for all the independent common SNPs across the human genome. If a p-value is found to be lower than this threshold in a genome-wide association study, the null hypot
brand slug: wiki
category slug: encyclopedia
description: Statistical significance threshold for genetic associations
original url: https://en.wikipedia.org/wiki/Genome-wide_significance
date created:
date modified: 2021-12-12T03:51:25Z
main entity: {"identifier":"Q85763011","url":"https://www.wikidata.org/entity/Q85763011"}
image:
fields total: 13
integrity: 14

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