GATA2 deficiency

id: gata2-deficiency-265-14521513
title: GATA2 deficiency
text: GATA2 deficiency is a grouping of several disorders caused by common defect, namely, familial or sporadic inactivating mutations in one of the two parental GATA2 genes. Being the gene haploinsufficient, mutations that cause a reduction in the cellular levels of the gene's product, GATA2, are autosomal dominant. The GATA2 protein is a transcription factor critical for the embryonic development, maintenance, and functionality of blood-forming, lymphatic-forming, and other tissue-forming stem cells
brand slug: wiki
category slug: encyclopedia
description: Medical condition
original url: https://en.wikipedia.org/wiki/GATA2_deficiency
date created:
date modified: 2024-03-05T15:23:36Z
main entity: {"identifier":"Q55612175","url":"https://www.wikidata.org/entity/Q55612175"}
image:
fields total: 13
integrity: 14

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