G418
id:
g418-205-6848175
title:
G418
text:
G418 (Geneticin) is an aminoglycoside antibiotic similar in structure to gentamicin B1. It is produced by Micromonospora rhodorangea. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. Resistance to G418 is conferred by the neo gene from Tn5 encoding an aminoglycoside 3'-phosphotransferase, APT 3' II. G418 is an analog of neomycin sulfate, and has similar mechanism as neomycin. G418 is commonly used in laboratory research to select genet
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/G418
date created:
2007-04-30T23:42:42Z
date modified:
2024-09-10T11:11:36Z
main entity:
{"identifier":"Q410036","url":"https://www.wikidata.org/entity/Q410036"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/03/G418.svg","width":158,"height":207}
fields total:
13
integrity:
16