G protein-coupled inwardly rectifying potassium channel
id:
g-protein-coupled-inwardly-rectifying-potassium-channel-286-8705860
title:
G protein-coupled inwardly rectifying potassium channel
text:
The G protein-coupled inwardly rectifying potassium channels (GIRKs) are a family of lipid-gated inward-rectifier potassium ion channels which are activated (opened) by the signaling lipid PIP2 and a signal transduction cascade starting with ligand-stimulated G protein-coupled receptors (GPCRs). GPCRs in turn release activated G-protein βγ- subunits (Gβγ) from inactive heterotrimeric G protein complexes (Gαβγ). Finally, the Gβγ dimeric protein interacts with GIRK channels to open them so that th
brand slug:
wiki
category slug:
encyclopedia
description:
Family of lipid-gated inward-rectifier potassium ion channels
original url:
https://en.wikipedia.org/wiki/G_protein-coupled_inwardly_rectifying_potassium_channel
date created:
date modified:
2023-05-23T23:15:28Z
main entity:
{"identifier":"Q3001168","url":"https://www.wikidata.org/entity/Q3001168"}
image:
fields total:
13
integrity:
14