FRS2
id:
frs2-316-15494482
title:
FRS2
text:
Fibroblast growth factor receptor substrate 2 is a protein that in humans is encoded by the FRS2 gene. FRS2 is an 80 kDa membrane-anchored signal transducing adaptor protein (STAP) that links specific activated Receptor Tyrosine Kinases (RTKs) to multiple downstream signaling pathways, most notably the MAPK/ERK, PI3K/AKT/mTOR and PLCγ pathways. It is overexpressed and amplified in several cancer types, including prostate cancer.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in humans
original url:
https://en.wikipedia.org/wiki/FRS2
date created:
date modified:
2024-03-27T19:13:00Z
main entity:
{"identifier":"Q18035859","url":"https://www.wikidata.org/entity/Q18035859"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/64/Protein_FRS2_PDB_1xr0.png","width":742,"height":365}
fields total:
13
integrity:
15