Flip–flop kinetics
id:
flip-flop-kinetics-259-7046716
title:
Flip–flop kinetics
text:
Flip–flop kinetics, or flip–flop pharmacokinetics, describes an atypical situation in pharmacokinetics where a drug's rate of absorption or the rate at which it enters the bloodstream is slower than its elimination rate. That is, when the ka is slower than ke. These circumstances can occur with sustained-release formulations, depot injections, and some subcutaneous or intradermal injections. In the resulting slope of log plasma concentration versus time, the apparent ke is determined by the ka,
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Flip%E2%80%93flop_kinetics
date created:
date modified:
2021-10-09T16:25:12Z
main entity:
{"identifier":"Q106322064","url":"https://www.wikidata.org/entity/Q106322064"}
image:
fields total:
13
integrity:
13