First-dose phenomenon
id:
first-dose-phenomenon-237-5464504
title:
First-dose phenomenon
text:
The first-dose phenomenon is a sudden and severe fall in blood pressure that can occur when changing from a lying to a standing position the first time that an alpha blocker drug is used or when resuming the drug after many months off. This postural hypotension usually happens shortly after the first dose is absorbed into the blood and can result in syncope (fainting). Syncope occurs in approximately 1% of patients given an initial dose of 2 mg prazosin or greater. This adverse effect is self-li
brand slug:
wiki
category slug:
encyclopedia
description:
Postural hypotension due to taking an alpha blocker drug
original url:
https://en.wikipedia.org/wiki/First-dose_phenomenon
date created:
date modified:
2023-11-08T06:47:30Z
main entity:
{"identifier":"Q5452192","url":"https://www.wikidata.org/entity/Q5452192"}
image:
fields total:
13
integrity:
14