FIASMA
id:
fiasma-243-955095
title:
FIASMA
text:
Functional inhibitors of acid sphingomyelinase, or FIASMA, is a large group of pharmacological compounds inhibiting the enzyme acid sphingomyelinase. This enzyme is mainly located within the lysosome, where it cleaves sphingomyelin to ceramide and sphingosine, the latter of which is then phosphorylated to sphingosine-1-phosphate. These metabolites, and subsequent inhibition of the enzyme, influence the balance between cell death (apoptosis) and cell growth (proliferation). A lack of regulation o
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/FIASMA
date created:
date modified:
2023-08-18T12:54:28Z
main entity:
{"identifier":"Q1388376","url":"https://www.wikidata.org/entity/Q1388376"}
image:
fields total:
13
integrity:
13