Farnesyltransferase
id:
farnesyltransferase-322-4399054
title:
Farnesyltransferase
text:
Farnesyltransferase is one of the three enzymes in the prenyltransferase group. Farnesyltransferase (FTase) adds a 15-carbon isoprenoid called a farnesyl group to proteins bearing a CaaX motif: a four-amino acid sequence at the carboxyl terminus of a protein. Farnesyltransferase's targets include members of the Ras superfamily of small GTP-binding proteins critical to cell cycle progression. For this reason, several FTase inhibitors are undergoing testing as anti-cancer agents. FTase inhibitors
brand slug:
wiki
category slug:
encyclopedia
description:
Enzyme in the prenyltransferase group
original url:
https://en.wikipedia.org/wiki/Farnesyltransferase
date created:
date modified:
2023-10-05T03:59:47Z
main entity:
{"identifier":"Q410994","url":"https://www.wikidata.org/entity/Q410994"}
image:
fields total:
13
integrity:
14