Familial amyloid cardiomyopathy
id:
familial-amyloid-cardiomyopathy-318-8169412
title:
Familial amyloid cardiomyopathy
text:
Familial amyloid cardiomyopathy (FAC), or transthyretin amyloid cardiomyopathy (ATTR-CM) results from the aggregation and deposition of mutant and wild-type transthyretin (TTR) protein in the heart. TTR is usually circulated as a homo-tetramer—a protein made up of four identical subunits—however, in FAC populations, TTR dissociates from this typical form and misassembles into amyloid fibrils which are insoluble and resistant to degradation. Due to this resistance to degradation, when amyloid fib
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Familial_amyloid_cardiomyopathy
date created:
date modified:
2023-08-22T14:15:01Z
main entity:
{"identifier":"Q5432929","url":"https://www.wikidata.org/entity/Q5432929"}
image:
fields total:
13
integrity:
14