Factor Inhibiting HIF Asparaginyl Hydroxylase Inhibitors
id:
factor-inhibiting-hif-asparaginyl-hydroxylase-inhibitors-237-11733460
title:
Factor Inhibiting HIF Asparaginyl Hydroxylase Inhibitors
text:
Factor Inhibiting HIF (FIH) Asparaginyl Hydroxylase Inhibitors inhibit the FIH pathway also catalyzed by Asparaginyl Hydroxylase inhibition. Before 2010s thought to be identical to HIF prolyl-hydroxylase pathway, studies have shown FIH to be the master regulator that controls HIF transcriptional activity in an oxygen-dependent manner. and that HIF prolyl-hydroxylase inhibitors may only minimally inhibit FIH. Skeletal muscle expresses 50-fold higher levels of FIH than other tissues. The cytoplasm
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wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Factor_Inhibiting_HIF_Asparaginyl_Hydroxylase_Inhibitors
date created:
date modified:
2023-02-16T07:11:01Z
main entity:
{"identifier":"Q110903676","url":"https://www.wikidata.org/entity/Q110903676"}
image:
fields total:
13
integrity:
13