Excitotoxicity
id:
excitotoxicity-176-18925189
title:
Excitotoxicity
text:
In excitotoxicity, nerve cells suffer damage or death when the levels of otherwise necessary and safe neurotransmitters such as glutamate become pathologically high, resulting in excessive stimulation of receptors. For example, when glutamate receptors such as the NMDA receptor or AMPA receptor encounter excessive levels of the excitatory neurotransmitter, glutamate, significant neuronal damage might ensue. Excess glutamate allows high levels of calcium ions (Ca2+) to enter the cell. Ca2+ influx
brand slug:
wiki
category slug:
encyclopedia
description:
Process that kills nerve cells
original url:
https://en.wikipedia.org/wiki/Excitotoxicity
date created:
2004-10-06T02:38:27Z
date modified:
2024-09-03T21:57:36Z
main entity:
{"identifier":"Q901117","url":"https://www.wikidata.org/entity/Q901117"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/7/7f/Low_Ca2%2B_buffering_and_excitotoxicity_under_physiological_stress_and_pathophysiological_conditions_in_motor_neuron_%28MNs%29.jpg","width":1200,"height":499}
fields total:
13
integrity:
16