Evans–Tishchenko reaction
id:
evans-tishchenko-reaction-238-6471627
title:
Evans–Tishchenko reaction
text:
The Evans–Tishchenko reaction is the diastereoselective reduction of β-hydroxy ketones to the corresponding 1,3-anti diol monoesters. The reaction employs a Lewis acid, often samarium iodide, and an aldehyde. It was first described in 1990 by David A. Evans and Amir Hoveyda, as a development of the well-known Tishchenko reaction discovered in 1906. The Aldol–Tishchenko reaction provides another potential route to 1,3-diol monoester products.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Evans%E2%80%93Tishchenko_reaction
date created:
date modified:
2022-01-07T15:34:29Z
main entity:
{"identifier":"Q11832882","url":"https://www.wikidata.org/entity/Q11832882"}
image:
fields total:
13
integrity:
13