ERA-45
id:
era-45-288-18395732
title:
ERA-45
text:
ERA-45 is a synthetic estrogen and a selective agonist of the ERα. It shows 286-fold selectivity for transactivation of the ERα over the ERβ, with EC50 values of 0.37 nM for the ERα and 13 nM for the ERβ. However, another found only about 35-fold potency for transactivation of the ERα over the ERβ. The drug has no antagonistic activity at either receptor. ERA-45 induced prostate cancer development in preclinical models when it was given in combination with testosterone, whereas testosterone alon
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/ERA-45
date created:
date modified:
2023-04-11T14:46:15Z
main entity:
{"identifier":"Q28209805","url":"https://www.wikidata.org/entity/Q28209805"}
image:
fields total:
13
integrity:
14