Entinostat
id:
entinostat-232-3759558
title:
Entinostat
text:
Entinostat, also known as SNDX-275 and MS-275, is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers. Entinostat inhibits class I HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM, respectively. Syndax pharmaceuticals currently holds the rights to entinostat and recently received $26.6 million in funds to advance treatments of resistant cancers using epigenetic tools. It has also been investigated as a potential male contraceptive drug.
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Entinostat
date created:
date modified:
2024-02-26T04:29:02Z
main entity:
{"identifier":"Q1281020","url":"https://www.wikidata.org/entity/Q1281020"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/c/c6/Entinostat.svg","width":512,"height":197}
fields total:
13
integrity:
15