Enhanced permeability and retention effect
id:
enhanced-permeability-and-retention-effect-249-17912928
title:
Enhanced permeability and retention effect
text:
The enhanced permeability and retention (EPR) effect is a controversial concept by which molecules of certain sizes tend to accumulate in tumor tissue much more than they do in normal tissues. The general explanation that is given for this phenomenon is that, in order for tumor cells to grow quickly, they must stimulate the production of blood vessels. VEGF and other growth factors are involved in cancer angiogenesis. Tumor cell aggregates as small as 150–200 μm, start to become dependent on blo
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Enhanced_permeability_and_retention_effect
date created:
date modified:
2022-12-05T08:19:15Z
main entity:
{"identifier":"Q1275685","url":"https://www.wikidata.org/entity/Q1275685"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/c/cf/Enhanced_permeability_and_retention_%28EPR%29_effect_and_passive_targeting.svg","width":512,"height":256}
fields total:
13
integrity:
14