Endoreduplication

id: endoreduplication-216-3573883
title: Endoreduplication
text: Endoreduplication is replication of the nuclear genome in the absence of mitosis, which leads to elevated nuclear gene content and polyploidy. Endoreduplication can be understood simply as a variant form of the mitotic cell cycle (G1-S-G2-M) in which mitosis is circumvented entirely, due to modulation of cyclin-dependent kinase (CDK) activity. Examples of endoreduplication characterised in arthropod, mammalian, and plant species suggest that it is a universal developmental mechanism responsible
brand slug: wiki
category slug: encyclopedia
description: Replication of the nuclear genome without mitosis
original url: https://en.wikipedia.org/wiki/Endoreduplication
date created: 2005-08-19T16:42:55Z
date modified: 2024-09-12T21:10:46Z
main entity: {"identifier":"Q1340781","url":"https://www.wikidata.org/entity/Q1340781"}
image:
fields total: 13
integrity: 15

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