End-sequence profiling
id:
end-sequence-profiling-273-6477308
title:
End-sequence profiling
text:
End-sequence profiling (ESP) is a method based on sequence-tagged connectors developed to facilitate de novo genome sequencing to identify high-resolution copy number and structural aberrations such as inversions and translocations. Briefly, the target genomic DNA is isolated and partially digested with restriction enzymes into large fragments. Following size-fractionation, the fragments are cloned into plasmids to construct artificial chromosomes such as bacterial artificial chromosomes (BAC) w
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/End-sequence_profiling
date created:
date modified:
2023-12-03T00:32:20Z
main entity:
{"identifier":"Q19904064","url":"https://www.wikidata.org/entity/Q19904064"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/1/18/Working_flow_ESP.jpeg","width":1278,"height":818}
fields total:
13
integrity:
14