Eliprodil

id: eliprodil-184-14728384
title: Eliprodil
text: Eliprodil (codenamed SL-82.0715) is an NMDA antagonist drug candidate which selectively inhibits the NR2B (GLUN2B) subtype NMDA receptor at submicromolar concentrations. Eliprodil failed a Phase III clinical trial for the treatment of acute ischemic stroke in 1996, sponsored by Synthélabo Recherche. NMDA receptors are a key component in mediating glutamate-induced excitotoxicity, and it is believed that NMDA antagonists would be neuroprotective after a stroke or other traumatic brain injury. Aft
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/Eliprodil
date created: 2008-07-20T07:48:28Z
date modified: 2024-09-07T17:31:12Z
main entity: {"identifier":"Q5361298","url":"https://www.wikidata.org/entity/Q5361298"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/ab/Eliprodil.svg","width":512,"height":180}
fields total: 13
integrity: 16

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