EIF2B
id:
eif2b-320-9727235
title:
EIF2B
text:
eIF2B is a protein complex found in eukaryotes. It is the guanine nucleotide exchange factor for the eukaryotic initiation factor 2 and therefore converts the inactive eIF2-GDP to the active eIF2-GTP. This activation is hindered by phosphorylation of the alpha subunit of eIF2, which leads to a stable eIF2α-P-GDP-eIF2B complex and therefore inhibits translation initiation. Human genes which encode eIF-2B proteins include: EIF2B1 – alpha subunit (26kDa)
EIF2B2 – beta subunit (39kDa)
EIF2B3 – gamma
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/EIF2B
date created:
date modified:
2021-01-24T05:36:42Z
main entity:
{"identifier":"Q5323146","url":"https://www.wikidata.org/entity/Q5323146"}
image:
fields total:
13
integrity:
13