EIF-2 kinase
id:
eif-2-kinase-233-10505189
title:
EIF-2 kinase
text:
eIF-2-alpha kinase is a kinase enzyme that phosphorylates eIF2α. There are four forms in mammals: EIF2AK1: heme-regulated inhibitor kinase (HRI)
EIF2AK2: the double-stranded RNA-dependent kinase
EIF2AK3: also known as "PKR-like endoplasmic reticulum kinase" (PEK/PERK)
EIF2AK4: also known as GCN2 These are all responsible for the phosphorylation of the alpha subunit of eIF-2 at serine 51, one of the best-characterized mechanisms for down-regulating protein synthesis in eukaryotes as a part of cel
brand slug:
wiki
category slug:
encyclopedia
description:
Protein serine/threonine kinase that is induced by interferon
original url:
https://en.wikipedia.org/wiki/EIF-2_kinase
date created:
date modified:
2024-01-09T02:59:12Z
main entity:
{"identifier":"Q5323131","url":"https://www.wikidata.org/entity/Q5323131"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/b3/EIF2regulation.jpg","width":323,"height":333}
fields total:
13
integrity:
15