E-64
id:
e-64-323-17861128
title:
E-64
text:
E-64 is an epoxide which can irreversibly inhibit a wide range of cysteine peptidases. The compound was first isolated and identified from Aspergillus japonicus in 1978. It has since been shown to inhibit many cysteine peptidases such as papain, cathepsin B, cathepsin L, calpain and staphopain. The low toxic effects of the inhibitor, in addition to its effective mechanism of action, makes E-64 a potential template for drugs to treat diseases where high levels of a cysteine proteases are the prim
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/E-64
date created:
date modified:
2022-12-19T14:05:41Z
main entity:
{"identifier":"Q5321373","url":"https://www.wikidata.org/entity/Q5321373"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/ba/E-64spheres.png","width":640,"height":434}
fields total:
13
integrity:
15