E-52862
id:
e-52862-324-3500490
title:
E-52862
text:
E-52862, also known as sigma-1 receptor antagonist, as well as MR-309, is a selective sigma-1 receptor antagonist, with a reported binding affinity of Ki = 17.0 ± 7.0 nM, selective over the sigma-2 receptor and against a panel of other 170 receptors, enzymes, transporters and ion channels. In preclinical studies, S1RA has demonstrated efficacy in relieving neuropathic pain and pain in other sensitizing conditions, associated with an improvement of the emotional negative state. S1RA is being deve
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/E-52862
date created:
date modified:
2023-11-07T08:42:42Z
main entity:
{"identifier":"Q7388203","url":"https://www.wikidata.org/entity/Q7388203"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/f/f4/S1RA.png","width":1123,"height":1290}
fields total:
13
integrity:
15