DUT (gene)
id:
dut-gene-263-8687142
title:
DUT (gene)
text:
DUTP pyrophosphatase, also known as DUT, is an enzyme which in humans is encoded by the DUT gene on chromosome 15. This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotrimeric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/DUT_(gene)
date created:
date modified:
2024-03-28T22:50:48Z
main entity:
{"identifier":"Q17915106","url":"https://www.wikidata.org/entity/Q17915106"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/3/3d/Protein_DUT_PDB_1q5h.png","width":796,"height":797}
fields total:
13
integrity:
15