DPH1
id:
dph1-315-18296896
title:
DPH1
text:
Diphthamide biosynthesis protein 1 is a protein that in humans is encoded by the DPH1 gene. It encodes a protein that performs posttranslational modification of histidine-715 on eukaryotic translation elongation factor 2 to diphthamide. This modification appears to be important in the translation of Cyclin D in ovarian cells. DPH1 is mutated in 90% of ovarian cancers end stage, usually by loss of heterozygosity.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/DPH1
date created:
date modified:
2022-10-13T20:33:15Z
main entity:
{"identifier":"Q17914176","url":"https://www.wikidata.org/entity/Q17914176"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/00/Ideogram_human_chromosome_17.svg","width":474,"height":189}
fields total:
13
integrity:
15