DPA-714
id:
dpa-714-275-15840293
title:
DPA-714
text:
DPA-714 or N,N-diethyl-2-[4-(2-fluoroethoxy)phenyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-acetamide is a selective ligand for the translocator protein (TSPO) currently under evaluation for several clinical applications. For this reason, a practical, multigram synthetic route for its preparation has been described. The binding affinity of DPA-714 for TSPO is reported as Ki = 7.0 ± 0.4 nM. [18F]DPA-714 is currently under investigation as a potential radiopharmaceutical for imaging TSPO in living
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/DPA-714
date created:
date modified:
2023-11-12T19:19:40Z
main entity:
{"identifier":"Q5205913","url":"https://www.wikidata.org/entity/Q5205913"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/a7/DPA-714_Structure.svg","width":1913,"height":1339}
fields total:
13
integrity:
15