Dowd–Beckwith ring-expansion reaction
id:
dowd-beckwith-ring-expansion-reaction-228-2186334
title:
Dowd–Beckwith ring-expansion reaction
text:
The Dowd–Beckwith ring-expansion reaction is an organic reaction in which a cyclic carbonyl is expanded by up to 4 carbons in a free radical ring expansion reaction through an α-alkylhalo substituent. The radical initiator system is based on azobisisobutyronitrile and tributyltin hydride. The cyclic β-keto ester can be obtained through a Dieckmann condensation. The original reaction consisted of a nucleophilic aliphatic substitution of the enolate of ethyl cyclohexanone-2-carboxylate with 1,4-di
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Dowd%E2%80%93Beckwith_ring-expansion_reaction
date created:
2005-11-23T21:57:31Z
date modified:
2024-09-15T09:39:54Z
main entity:
{"identifier":"Q5302672","url":"https://www.wikidata.org/entity/Q5302672"}
image:
fields total:
13
integrity:
14