Donor-specific antibody
id:
donor-specific-antibody-233-12873910
title:
Donor-specific antibody
text:
Donor-specific antibodies (DSA) are a concept in transplantation medicine and describe the presence of antibodies specific to the Donor's HLA-Molecules. These antibodies can cause antibody-mediated rejection and are therefore considered a contraindication against transplantation in most cases. DSA are a result of B cell and plasma cell activation and bind to HLA and/or non-HLA molecules on the endothelium of the graft. They were first described in 1969 by Patel et al., who found that Transplant
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Donor-specific_antibody
date created:
date modified:
2023-02-22T12:39:48Z
main entity:
{"identifier":"Q48928650","url":"https://www.wikidata.org/entity/Q48928650"}
image:
fields total:
13
integrity:
13